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What is Geotagging?
What is Geotagging?
Geotagging or geocoding is a way to add geographical meta data to photos, RSS feeds, and websites. A geotag can define the longitude and latitude of the tagged item. Or it can define the location place name or regional identifier. It can also include information such as the altitude and bearing.

Transcriptional Factors And Regulators.

All the cellular processes in living cells such as growth, development, morphogenesis and cellular differentiation are a product of gene expression programs involving complicated transcriptional regulation of several genes. This process of transcriptional regulation is tightly controlled and coordinated by proteins called transcriptional regulators. These transcriptional regulators and factors are DNA-binding proteins that bind to the promoter or enhancer sequences on the DNA and facilitate either transcriptional repression or activation.

RNA interference: Imgenex launched the pSuppressor Adeno construction kit for adenovirus mediated gene knockdown.

RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals. The RNAi pathway is thought to be an ancient mechanism for protecting the host and its genome against viruses and rogue genetic elements that use double-stranded RNA (dsRNA) in their life cycles. They have also been shown to play a role not only in mRNA and dsRNA stability/degradation, but also in regulation of translation, transcription, chromatin structure, and genome integrity.

Regulatory T Cells (Treg)

Early development and differentiation of nascent T cells that migrate from bone marrow to become mature, naïve T cells, which are capable of responding to antigen takes place inside the thymus. Around 1010 TCR (T cell receptor) variations are generated in developing T lymphocyte clones through a random process of somatic cell gene reorganization. During this process, often T-cells recognizing self-antigens are generated. Due to the ability of these self-reactive T-cells to elicit an autoimmune attack, they are permanently removed by the thymus through negative selection and clonal deletion.

Fundamental Immunology, Basic Immunology and Allergy Immunology

Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. The immune system is the body's defense against infectious organisms and other invaders. Through a series of steps called the immune response, the immune system attacks organisms and substances that invade our systems and cause disease. The immune system is made up of a network of cells, tissues, and organs that work together to protect the body. The immune system is the body’s natural defence in combating organisms.

New FOXP3Δ2 (Exon 2 Deleted) Specific Antibody

FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function. FOXP3 significance in the normal development of Tregs is better elucidated with the fact that mutated FOXP3 results in a rare and fatal early onset autoimmune disorder in humans called XLAAD/IPEX (human immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome), a condition phenotypically similar to Scurfy in mice.

Faces of DARPP-32: Master Signaling Mediator in the Brain?

As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act either as a phosphatase or kinase inhibitor in a contextually dependent manner. Growing evidence points to DARPP-32 as a key mediator/modulator in numerous signal transduction cascades implicated in a growing number of neurological disorders such as schizophrenia and depression, as well as in drug abuse and addiction.

ATM (Ataxia Telangiectasia Mutated) Antibodies from Imgenex

ATM, the gene product mutated in the cancer susceptibility syndrome ataxia–telangiectasia, is related to proteins involved in DNA repair and cell-cycle control. It encodes a nuclear 350 kDa phosphoprotein containing a carboxy terminus phosphatidylinositol 3-kinase (Pl-3 kinase) catalytic domain shared by members of a superfamily of large eukaryotic proteins involved in intracellular signaling, DNA-damage induced cell cycle checkpoints, DNA repair and recombination.

Apoptosis Programmed Cell Death.

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). For more details read out the article:

Akt Family: Antibodies from Imgenex

Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are important molecules in mammalian cellular signaling. The three widely expressed isoforms of PKB (PKB , PKBß and PKB ; also known as Akt1, Akt2 and Akt3, respectively) are each composed of an N-terminal PtdIns(3,4,5)P3- and PtdIns(3,4)P2-binding PH domain and a C-terminal kinase catalytic domain.

Actin Antibody Available in Imgenex now

Actin is a ubiquitous protein involved in the formation of filaments that are major components of the cytoskeleton. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments which are part of the contractile apparatus in muscle cells. It is the most abundant protein in the typical eukaryotic cell, accounting for about 15% in some cell types. The protein is highly conserved, and forms a huge variety of structure in cells in concert with a huge numbers of actin binding proteins.

NetSetMan - a good IP address switching tool

NetSetMan - a good IP address switching tool

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marcel's picture
NASA no longer wants to understand and protect our home planet

In early February, NASA reportedly eliminated the words "to understand and protect our home planet" from its mission statement.

That's all we have to say.

Ultralight Boat Dances on Waves Like a Spider

In Greek mythology, Proteus was a sea god capable of assuming different forms. And now Proteus also is the name of a new type of ocean-going ship that can adapt its shape to the motion of the sea.

A hush-hush project to develop a new type of ocean vessel was introduced last week, when a prototype called “Proteus” made its way across San Francisco Bay.

Ugo Canti is its inventor and captain. "Now, finally we are ready for this preview," he said.

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